ARP7048-01 [Polyclonal Antibody]
TGFBR2 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IF
Immunogen Range:   A recombinant protein of human TGFBR2
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   7048
Swiss Prot:   P37173
Synonyms:   AAT3, FAA3, MFS2, RIIC, LDS1B, LDS2B, TAAD2, TGFR-2, TGFbeta-RII
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.
Caculated MW:   65 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
IF 1:50-1:200
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information