
| Species: | Rabbit | 
| Applications: | WB IHC IF | 
| Immunogen Range: | A recombinant protein of human HFE | 
| Clonality: | Polyclonal Antibody | 
| Isotype: | IgG | 
| GENE ID: | 3077 | 
| Swiss Prot: | Q30201 | 
| Synonyms: | HH, HFE1, HLA-H, MVCD7, TFQTL2, MGC103790,dJ221C16.10.1 | 
| Purification: | Affinity purification | 
| Storage: | Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. | 
| Background: | The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. [provided by RefSeq, Jul 2008] | 
| Caculated MW: | 40kDa | 
| Observed MW: | Refer to Figures | 
| Applications: | 
                                WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50- 1:200  | 
                        
| Reacitivity: | Human |