Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | A recombinant protein of human HFE |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 3077 |
Swiss Prot: | Q30201 |
Synonyms: | HH, HFE1, HLA-H, MVCD7, TFQTL2, MGC103790,dJ221C16.10.1 |
Purification: | Affinity purification |
Storage: | Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: | The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. [provided by RefSeq, Jul 2008] |
Caculated MW: | 40kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50- 1:200 |
Reacitivity: | Human |