Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | A synthetic peptide of human PTGS2 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 5743 |
Swiss Prot: | P35354 |
Synonyms: | PTGS2, COX2, Prostaglandin G/H synthase 2, Cyclooxygenase-2, PHS II, Prostaglandin H2 synthase 2, Prostaglandin-endoperoxide synthase 2 |
Purification: | Affinity purification |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. |
Caculated MW: | 70 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:200-1:500 IHC 1:50-1:100 IF 1:20-1:50 |
Reacitivity: | Human |