Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | A recombinant protein of human ATXN3 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 4287 |
Swiss Prot: | P54252 |
Synonyms: | ATXN3,AT3,ATX3,JOS,MJD,MJD1,SCA3 |
Purification: | Affinity purification |
Storage: | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: | Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Sep 2009] |
Caculated MW: | 43kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
Reacitivity: | Human, Mouse, Rat |