Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | A recombinant protein of human ALDH2 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 217 |
Swiss Prot: | P05091 |
Synonyms: | ALDH-E2,ALDHI,ALDM,MGC1806 |
Purification: | Affinity purification |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | Acetaldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. It mediates NADP+-dependent oxidation of aldehydes into acids during detoxification of alcohol-derived acetaldehyde; lipid peroxidation; and metabolism of corticosteroids, biogenic amines and neurotransmitters. Genetic variation in ALDH2 is responsible for individual differences in responses to drinking alcohol. Thus, the absence of this enzyme is linked to alcohol intolerance and a reduced risk for alcoholism-related liver disease. |
Caculated MW: | 56 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200 |
Reacitivity: | Human, Mouse, Rat |