Species: | Rabbit |
Applications: | WB IHC ICC IF IP |
Immunogen Range: | A recombinant protein of human CD86 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 942 |
Swiss Prot: | P42081 |
Synonyms: | CD86,B7-2,B70,CD28LG2,LAB72,MGC34413 |
Purification: | Affinity purification |
Storage: | Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: | This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011] |
Caculated MW: | 38kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50- 1:100 ICC 1:50- 1:100 |
Reacitivity: | Human, Mouse |