ARP942-01 [Polyclonal Antibody]
CD86 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC ICC IF IP
Immunogen Range:   A recombinant protein of human CD86
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   942
Swiss Prot:   P42081
Synonyms:   CD86,B7-2,B70,CD28LG2,LAB72,MGC34413
Purification:   Affinity purification
Storage:   Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background:   This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]
Caculated MW:   38kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50- 1:100
ICC 1:50- 1:100
Reacitivity:   Human, Mouse
For research use only. Not intended for diagnostic or therapeutic use!
Additional information