ARP29085-01 [Polyclonal Antibody]
PHPT1 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF
Immunogen Range:   A recombinant protein of human PHPT1
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   29085
Swiss Prot:   Q9NRX4
Synonyms:   PHPT1,CGI-202,DKFZp564M173,HSPC141,PHP14,bA216L13.10
Purification:   Affinity purification
Storage:   Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background:   PHPT1 (Phosphohistidine phosphatase 1), also known as 14 kDa phosphohistidine phosphatase, is a 125 amino acid enzyme belonging to the Janus protein family. Existing as a monomer in the cytoplasm, PHPT1 is an EDTA-insensitive phosphohistidine phosphatase. First identified in human adrenal gland, PHPT1 is highly expressed in skeletal muscle and heart, with lower expression in liver, pancreas and kidney. Overexpression of PHPT1 leads to specific phosphohistidine phosphatase activity towards phosphopeptide I, with no activity detected towards phosphotyrosine, phosphothreonine and phosphoserine peptides. PHPT1 is highly conserved among species, suggesting that it serves an essential functional role.
Caculated MW:   14kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information