Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | A recombinant protein of human CUL3 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 8452 |
Swiss Prot: | Q13618 |
Synonyms: | CUL-3, PHA2E |
Purification: | Affinity purification |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | CUL3 (Cullin-3) is a member of the cullin-based ubiquitin ligase family. By interacting with Hrt1 and BTB domain containing proteins, the complex functions as a CUL3-based E3 ligase to bring specific substrates to ubiquitinylation and degradation (1). The CUL3 complex has been shown to target many substrates involved in cell cycle progression (2), transcription (3), development and differentiation (4,5). |
Caculated MW: | 89 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200 |
Reacitivity: | Human, Mouse, Rat |