Species: | Rabbit |
Applications: | WB IHC IF ICC |
Immunogen Range: | A recombinant protein of human KRT8 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 5087 |
Swiss Prot: | P05787 |
Synonyms: | KRT8, CARD2, CK8, CYK8, K2C8, K8, KO |
Purification: | Affinity purification |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | Keratins (cytokeratins) are intermediate filament proteins that are mainly expressed in epithelial cells. Keratin heterodimers composed of an acidic keratin (or type I keratin, keratins 9 to 23) and a basic keratin (or type II keratin, keratins 1 to 8) assemble to form filaments (1,2). Keratin isoforms demonstrate tissue- and differentiation-specific profiles that make them useful as biomarkers (1). Research studies have shown that mutations in keratin genes are associated with skin disorders, liver and pancreatic diseases, and inflammatory intestinal diseases (3-6). |
Caculated MW: | 54 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200 ICC 1:50-1:100 |
Reacitivity: | Human, Mouse, Rat |