Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | A recombinant protein of human HSPD1 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 3329 |
Swiss Prot: | P10809 |
Synonyms: | HSPD1, CPN60, GROEL, HLD4, HSP60, HSP65, HuCHA60, SPG13 |
Purification: | Affinity purification |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | In both prokaryotic and eukaryotic cells the misfolding and aggregation of proteins during biogenesis and under conditions of cellular stress are prevented by molecular chaperones (1-3). HSP60 has primarily been known as a mitochondrial protein that is important for folding key proteins after import into the mitochondria (4). It is now clear that a significant amount of HSP60 is also present in the cytosol of many cells and that it is induced by stress, inflammatory and immune responses, autoantibodies correlated with Alzheimer's, coronary artery diseases, MS, and diabetes (5-8). |
Caculated MW: | 61 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200 |
Reacitivity: | Human, Mouse |