ARP4683-01 [Polyclonal Antibody]
NBN Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IF FC
Immunogen Range:   A synthetic peptide of human NBN
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   4683
Swiss Prot:   O60934
Synonyms:   ATV, NBS, P95, NBS1, AT-V1, AT-V2
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.
Caculated MW:   62 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:1000
IF 1:20-1:50
FC 1:20-1:50
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information