Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | A fusion protein of human EIF2A |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 1965 |
Swiss Prot: | P05198 |
Synonyms: | EIF2, EIF-2, EIF2A, EIF-2A, EIF-2alpha |
Purification: | Affinity purification |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S28), and the 52-kD EIF2-gamma subunit (EIF2S3). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha. |
Caculated MW: | 36 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:1000 IHC 1:50-1:100 IF 1:20-1:50 |
Reacitivity: | Human, Mouse, Rat |