Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | A recombinant protein of human CDC37 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 11140 |
Swiss Prot: | Q16543 |
Synonyms: | CDC37A, P50CDC37, Hsp90 co chaperone Cdc37 |
Purification: | Affinity purification |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | Cdc (cell division control) family of proteins are regulatory proteins involved in the processes of cell cycle and proliferation. Cdc37, migrated as a protein of 50 kDa in SDS PAGE, is a co-chaperone protein that recruits several immature client kinases to Hsp90 for proper folding. It functions in association with Hsp90, although little is known of its mechanism of action or where it fits into a folding pathway involving other Hsp90 cochaperones. Cdc37 up-regulation is a common early event in some localized human cancers. But, the effect of Cdc37 dysregulation in human cells is unclear. |
Caculated MW: | 44 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:1000 IHC 1:50-1:100 IF 1:20-1:50 |
Reacitivity: | Human, Mouse, Rat |