ARP1072-01
[Polyclonal Antibody]
CFL1 Rabbit Polyclonal Antibody
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Species: |
Rabbit |
Applications: |
WB IHC |
Immunogen Range: |
A recombinant protein of human CFL1 |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
1072 |
Swiss Prot: |
P23528 |
Synonyms: |
CFL, CFL1, p18, Cofilin 1 |
Purification: |
Affinity purification |
Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus. |
Caculated MW: |
18 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500-1:1000 IHC 1:20-1:100
|
Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!