ARP12364-01 [Polyclonal Antibody]
CASP12 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF
Immunogen Range:   A synthetic peptide of human CASP12
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   12364
Swiss Prot:   Q6UXS9
Synonyms:   CASP12P1
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   Caspase 12 is an enzyme known as a cysteine protease. It belongs to a family of enzymes called caspases that cleave their substrates at C-terminal aspartic acid residues. It is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. Caspase-12 is located in the endoplasmic reticulum (ER). It is responsible for ER-stress-induced apoptosis, such as high calcium concentration, low oxygen and low glucose levels. Caspase-12 Antibody detects endogenous levels of full-length caspase-12 protein (50 kDa) and its cleaved product (40-44 kDa). This antibody does not cross-react with other caspases.
Caculated MW:   39 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:1000
IHC 1:20-1:200
IF 1:10-1:100
Reacitivity:   Human, Mouse
For research use only. Not intended for diagnostic or therapeutic use!
Additional information