
| Species: | Rabbit |
| Applications: | WB IHC IF FC |
| Immunogen Range: | A synthetic peptide of human XRCC1 |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 7515 |
| Swiss Prot: | P18887 |
| Synonyms: | RCC |
| Purification: | Affinity purification |
| Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: | The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. |
| Caculated MW: | 69 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:500-1:1000 IHC 1:50-1:100 IF 1:20-1:50 FC 1:20-1:50 |
| Reacitivity: | Human |