Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | A recombinant protein of human NUDT6 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 11162 |
Swiss Prot: | P53370 |
Synonyms: | NUDT6,ASFGF2,FGF-2,FGF-AS,FGF2AS,bFGF,gfg,gfg-1 |
Purification: | Affinity purification |
Storage: | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: | NUDT6 (nudix (nucleoside diphosphate linked moiety X)-type motif 6), also known as Antisense basic fibroblast growth factor or GFG-1, is a member of the Nudix hydrolase family of pyrophosphatases. Nudix hydrolases contain a characteristic Nudix domain and are responsible for catalyzing the hydrolysis of nucleoside diphosphate derivatives. The gene encoding NUDT6 is a FGF-2 gene antisense transcript, and NUDT6 is believed to regulate FGF-2 expression. FGF-2 is a mutifunctional heparin-binding growth factor important to angiogenesis, neuroectoderm development and wound healing. NUDT6 is expressed as two isoforms produced by alternative splicing. |
Caculated MW: | 36kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
Reacitivity: | Human, Mouse, Rat |