
| Species: | Rabbit |
| Applications: | WB IHC IP IF ChIP |
| Immunogen Range: | N term -peptide of human HDAC1 |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 3065 |
| Swiss Prot: | Q13547 |
| Synonyms: | DKFZp686H12203, GON-10, HD1, RPD3, RPD3L1 |
| Purification: | Affinity purification |
| Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: | Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. |
| Caculated MW: | 55 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200 ChIP 1:20-1:100 Dot 1:20-1:100 |
| Reacitivity: | Human, Mouse, Rat |