YRP10503-01
[Polyclonal Antibody]
CD3 Rabbit Polyclonal Antibody
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DATASHEET
| Species: |
Rabbit |
| Applications: |
IHC IF |
| Immunogen Range: |
KLH conjugated synthetic peptide derived from pig CD3E |
| Clonality: |
Polyclonal Antibody |
| Isotype: |
IgG |
| GENE ID: |
397455 |
| Swiss Prot: |
Q7YRN2 |
| Synonyms: |
CD3, T-cell surface glycoprotein CD3 epsilon chain, CD3e |
| Purification: |
Purified by Protein A. |
| Storage: |
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Background: |
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]. |
| Caculated MW: |
/ |
| Observed MW: |
Refer to Figures |
| Applications: |
IHC 1:100-1:500 IF 1:50-1:200
|
| Reacitivity: |
Pig |
For research use only. Not intended for diagnostic or therapeutic use!