Species: | Mouse |
Applications: | WB IHC IF |
Immunogen Range: | Full length native protein purified from human |
Clonality: | Monoclonal Antibody |
Isotype: | IgG |
GENE ID: | 354 |
Swiss Prot: | P07288 |
Synonyms: | APS, PSA, hK3, KLK2A1, Prostate-specific antigen, Gamma-seminoprotein, Seminin, Kallikrein-3, P-3 antigen, Semenogelase, KLK3 |
Purification: | Purified by Protein G. |
Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: | Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]. |
Caculated MW: | / |
Observed MW: | Refer to Figures |
Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 |
Reacitivity: | Human |