YMM00996-01
[Monoclonal Antibody]
HPV18 E6 protein (2F6) Mouse Monoclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Mouse |
| Applications: | IHC IF |
| Immunogen Range: | KLH conjugated synthetic peptide derived from HPV18 E6 protein |
| Clonality: | Monoclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 1489088 |
| Swiss Prot: | P06463 |
| Synonyms: | Protein E6, E6 |
| Purification: | Purified by Protein G. |
| Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Background: | Transcriptional transactivator. Binds double-stranded DNA (By similarity). Has transforming activity. Inactivates, with E6-AP ubiquitin-protein ligase, the human p53/TP53 tumor suppressor protein by targeting it to degradation. Binds and targets human MUPP1/MPDZ protein to degradation. Those two functions presumably contribute to transforming activity. Interaction with human FBLN1 protein also seems to be linked to cell transformation. |
| Caculated MW: | / |
| Observed MW: | Refer to Figures |
| Applications: |
IHC 1:100-1:500 IF 1:50-1:200 |
| Reacitivity: | Virus (HPV18) |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information