YRP09860-01 [Polyclonal Antibody]
SLN Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   IHC IF
Immunogen Range:   KLH conjugated synthetic peptide derived from human SLN/Sarcolipin
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   6588
Swiss Prot:  
Synonyms:   SARCO_HUMAN, Sarcolipin, SLN.
Purification:   Purified by Protein A.
Storage:   Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Background:   Sarcolipin is a 31 amino acid integral membrane protein belonging to the sarcolipin family. The gene encoding for the protein maps to chromosome 11q22-q23. SLN, localizing to the sarcoplasmic reticulum, regulates Ca-ATPase activity in skeletal muscle. It associates with calcium ATPase SERCA1 (Sarco(endo)plasmic reticulum Ca2+-ATPases). In muscle tissue, SERCAs are regulated by sarcolipin and another membrane protein, phospholamban (PLN). SLN is expressed in high levels in fast-twitch muscle, which has high expression of SERCA1a, and in lower levels in cardiac muscle. In rats, however, expression of SLN is higher in cardiac muscle than in fast-twitch muscle.
Caculated MW:   /
Observed MW:   Refer to Figures
Applications:   IHC 1:100-1:500
IF 1:50-1:200
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information