YRP09854-01 [Polyclonal Antibody]
BAALC Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF
Immunogen Range:   KLH conjugated synthetic peptide derived from human BAALC
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   79870
Swiss Prot:  
Synonyms:   BAALC, BAALC_HUMAN, Brain and acute leukemia cytoplasmic, Brain and acute leukemia cytoplasmic protein, brain and acute leukemia, cytoplasmic, FLJ12015.
Purification:   Purified by Protein A.
Storage:   Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Background:   BAALC is a 180 amino acid protein that localizes to both the membrane and the cytoplasm and exists as multiple alternatively spliced isoforms. Expressed by hematopoetic and neural cells, BAALC interacts with CaMKII and is thought to play a role in synaptic function at postsynaptic lipid rafts. BAALC may be overexpressed in acute myeloid leukemia (AML), suggesting a role in tumorigenesis. The gene encoding BAALC maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that maps to chromosome 8.
Caculated MW:   /
Observed MW:   Refer to Figures
Applications:   WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information